Science news reports that several groups started working on a vaccine for 2019-nCoV shortly after Chinese scientists shared the virus’s genetic sequence in an online public database on Jan. 10.
Three of these groups are funded by
Coalition for Epidemic Preparedness Innovations (CEPI), a nonprofit formed in 2017 to fund vaccine development for emerging infectious diseases.
Inovio Pharmaceuticals Inc. and Moderna Inc. both say they will have a vaccine ready for testing in animals in one month.
Moderna, which is working with the U.S. National Institute of Allergy and Infectious Diseases, estimates that it could have a vaccine ready for a phase one clinical trial in people in three months.
Moderna and Inovio are both using a newer vaccine technology based on specific DNA or messenger RNA (mRNA) sequences of the virus. The chosen sequence codes for a viral protein, such as one on the surface of the virus.
This type of vaccine can still elicit a protective immune response in a person. But because the protein is only a small piece of the virus, it doesn’t cause illness.
Scientists using this method can also start designing a vaccine as soon as they have the virus’s genetic sequence. With other methods, they would need to work with actual virus samples in the lab.
“The nice thing about this technology is that it bypasses many of the traditional steps to vaccine discovery and development. So it’s very fast,” said
Dr. Jon Andrus, adjunct professor of global vaccinology and vaccine policy at the
Milken Institute School of Public Health of George Washington University.
The third group, at the University of Queensland in Australia, is aiming to have a vaccine ready for testing in people in 16 weeks. They are developing a vaccine by growing viral proteins in cell cultures.
Drugmaker Johnson and Johnson, which is not funded by CEPI, started working on a vaccine two weeks ago,
according to CNBC. The company’s chief scientific officer estimates they could have a vaccine ready for market within a year.
https://www.healthline.com/health-n...ne-for-coronavirus#Faster-vaccine-development